Study Finds Women With Lupus Successful Pregnancy

Studies made from multi-center National Institute of Health founded PROMISSE Initiative in American College of Rheumatology on its 2011 yearly Scientific Meeting held in Chicago showed that women who suffered from stable lupus can still get pregnant.

There was misconceptions based in the outdated experience about women having lupus shouldn’t try to get pregnant. Now there are treatments that give better understanding about the disease. They can now identify when pregnancy is not dangerous for both mother and the fetus.

Majority of women with lupus defined limited activities and no flare in their time of pregnancy and in the first trimesters, has good conceptions. This is explained by Dr. Salmon, one of the main researchers of PROMISSE study. They learn that good timing is the main element for triumphant pregnancy for lupus patient.

There are two groups of complications assessed in the study, they are: health of fetus and wellbeing of the mother. Research teams reviewed the development of moderate, mild and severe lupus increase activity or flares, for pregnant women. For fetus, research examined worst outcomes like fatality or cases which the condition of the baby will need extended hospitalization in ICU.

In 333 women suffering from lupus, only 63 have poor results. 10% of mothers suffered pre-eclampsia, serious complications characterized by onset hypertension and existence of protein in urines. 10% experience moderate and mild flares at twenty weeks and 8% suffered flares in 32 weeks.

PROMISSE study established by the nationwide Institute of Arthritis, the Musculoskeletal and Skin Disease of National Institute of Health in year 2003 identified biomarkers that will predict poor pregnancy outcome in lupus patients. So far, PROMISSE investigation team enrolled 647 volunteer who’re monitored with on-month check-ups and research lab studies circulating proteins and genes that can predict the way of pregnancy.

PROMISSE continue through 2013 amid $12.3 millions of support over 10 years from the NIAMS and the Research in Women Health office. Salmon and the others continue to study a range of molecular pathways and genes that could affects women pregnancy for pre-eclampsia and miscarriage in healthy women.

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